Hirose M, Inada K.
Postoperative deep vein thrombosis-early diagnosis and prophylaxis.
Jpn Circ J 1984 Jan;48(1):111-7

The incidence of postoperative deep vein thrombosis (DVT) was investigated using
the 125I-fibrinogen method and measurement of beta-thromboglobulin on surgical and
gynecological patients. It was definitely lower in Japan as compared to Western
countries. The age of 50 or more and malignant diseases were significant as risk
factors for development of DVT. The presence of hypercoagulability before surgery
and on the first postoperative day in addition to postoperative impaired
fibrinolysis was considered to be the most important factor in development of
DVT. The efficacy of the graded compression stocking for the prevention of DVT
was confirmed, reducing from 13.5 per cent to 4.0 per cent. Furthermore, the most
effective preventive method is the use of an intermittent pneumatic compression
device for high risk patients with DVT.