Koike S.
[Study on postoperative deep venous thrombosis with reference to prevention]
Nippon Geka Gakkai Zasshi 1988 Feb;89(2):270-81

First Department of Surgery, Gifu University School of Medicine, Japan.

Preventive effect of intermittent sequential pneumatic compression of the legs
(ISPC) on the postoperative deep venous thrombosis (DVT) was studied by
125I-fibrinogen uptake test in 64 surgical patients. Furthermore the mechanism of
preventive effect by ISPC was analysed from the point of view of coagulation and
fibrinolytic activity in 78 patients. Following results were obtained. 1) The
incidence of DVT in control group was 18.0 percent, while it was 6.3 percent in
ISPC group (p less than 0.01). 2) The euglobulin lysis time in ISPC group was
significantly shorter than that of control group on the first postoperative day
(p less than 0.01). 3) There were no definite changes in plasminogen and B beta
15-42 peptide between control group and ISPC group. 4) There were no
complications in using of ISPC. This study demonstrates that ISPC has a dual
action; (1) mechanical prevention of venous stasis and (2) fibrinolytic
acceleration. ISPC are effective for prevention of postoperative DVT.